Journal Articles

Use of NSAIDS
Anthony, J. C., Breitner, J. C., Zandi, P. P., Meyer, M. R., Jurasova, I., Norton, M. C., et al. (2000). Reduced prevalence of AD in users of NSAIDs and H2 receptor antagonists: the Cache County study. Neurology, 54(11), 2066-2071.
Hayden, K. M., Zandi, P. P., Khachaturian, A. S., Szekely, C. A., Fotuhi, M., Norton, M. C., et al. (2007). Does NSAID use modify cognitive trajectories in the elderly? The Cache County study. Neurology, 69(3), 275-282.
Zandi, P. P., Anthony, J. C., Hayden, K. M., Mehta, K., Mayer, L., & Breitner, J. C. (2002). Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study. Neurology, 59(6), 880-886.
 
Vitamin Use
Hayden, K., Zandi, P., Lyketsos, C. G., Khachaturian, A., Bastian, L. A., Charoonruk, G., et al. (2007). Risk of mortality with vitamin E supplements. The Cache County Study. Am J Med, 120(2), 180-184.
Wengreen, H. J., Munger, R. G., Corcoran, C. D., Zandi, P., Hayden, K. M., Fotuhi, M., et al. (2007). Antioxidant intake and cognitive function of elderly men and women: the Cache County Study. J Nutr Health Aging, 11(3), 230-237.
Zandi, P. P., Anthony, J. C., Khachaturian, A. S., Stone, S. V., Gustafson, D., Tschanz, J. T., et al. (2004). Reduced risk of Alzheimer disease in users of antioxidant vitamin supplements: the Cache County Study. Arch Neurol, 61(1), 82-88.
 
Depression
Norton, M. C., Skoog, I., Toone, L., Corcoran, C., Tschanz, J. T., Lisota, R. D., et al. (2006). Three-year incidence of first-onset depressive syndrome in a population sample of older adults: the Cache County study. Am J Geriatr Psychiatry, 14(3), 237-245.
Steffens, D. C., Otey, E., Alexopoulos, G. S., Butters, M. A., Cuthbert, B., Ganguli, M., et al. (2006). Perspectives on depression, mild cognitive impairment, and cognitive decline. Arch Gen Psychiatry, 63(2), 130-138.
Steffens, D. C., Skoog, I., Norton, M. C., Hart, A. D., Tschanz, J. T., Plassman, B. L., et al. (2000). Prevalence of depression and its treatment in an elderly population: the Cache County study. Arch Gen Psychiatry, 57(6), 601-607.
 
Hormone Replacement Therapy
Breitner, J. C., & Zandi, P. P. (2003). Effects of estrogen plus progestin on risk of dementia. Jama, 290(13), 1706-1707; author reply 1707-1708.
Carlson, M. C., Zandi, P. P., Plassman, B. L., Tschanz, J. T., Welsh-Bohmer, K. A., Steffens, D. C., et al. (2001). Hormone replacement therapy and reduced cognitive decline in older women: the Cache County Study. Neurology, 57(12), 2210-2216.
Steffens, D. C., Norton, M. C., Plassman, B. L., Tschanz, J. T., Wyse, B. W., Welsh-Bohmer, K. A., et al. (1999). Enhanced cognitive performance with estrogen use in nondemented community-dwelling older women. J Am Geriatr Soc, 47(10), 1171-1175.
Zandi, P. P., Carlson, M. C., Plassman, B. L., Welsh-Bohmer, K. A., Mayer, L. S., Steffens, D. C., et al. (2002). Hormone replacement therapy and incidence of Alzheimer disease in older women: the Cache County Study. Jama, 288(17), 2123-2129
 
Apolipoprotein E genotype
Bigler, E. D., Lowry, C. M., Anderson, C. V., Johnson, S. C., Terry, J., & Steed, M. (2000). Dementia, quantitative neuroimaging, and apolipoprotein E genotype. AJNR Am J Neuroradiol, 21(10), 1857-1868.
Bigler, E. D., Tate, D. F., Miller, M. J., Rice, S. A., Hessel, C. D., Earl, H. D., et al. (2002). Dementia, asymmetry of temporal lobe structures, and apolipoprotein E genotype: relationships to cerebral atrophy and neuropsychological impairment. J Int Neuropsychol Soc, 8(7), 925-933.
Breitner, J. C., Wyse, B. W., Anthony, J. C., Welsh-Bohmer, K. A., Steffens, D. C., Norton, M. C., et al. (1999). APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study. Neurology, 53(2), 321-331.
Hayden, K. M., Zandi, P. P., Lyketsos, C. G., Tschanz, J. T., Norton, M. C., Khachaturian, A. S., et al. (2005). Apolipoprotein E genotype and mortality: findings from the Cache County Study. J Am Geriatr Soc, 53(6), 935-942.
Khachaturian, A. S., Corcoran, C. D., Mayer, L. S., Zandi, P. P., & Breitner, J. C. (2004). Apolipoprotein E epsilon4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study. Arch Gen Psychiatry, 61(5), 518-524.
Meyer, M. R., Tschanz, J. T., Norton, M. C., Welsh-Bohmer, K. A., Steffens, D. C., Wyse, B. W., et al. (1998). APOE genotype predicts when--not whether--one is predisposed to develop Alzheimer disease. Nat Genet, 19(4), 321-322.
Steffens, D. C., Norton, M. C., Hart, A. D., Skoog, I., Corcoran, C., & Breitner, J. C. (2003). Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study. Psychol Med, 33(3), 541-547.
 
Brain Imaging & Brain Banking
Bigler, E. D., Kerr, B., Victoroff, J., Tate, D. F., & Breitner, J. C. (2002). White matter lesions, quantitative magnetic resonance imaging, and dementia. Alzheimer Dis Assoc Disord, 16(3), 161-170.
Bigler, E. D., Lowry, C. M., Kerr, B., Tate, D. F., Hessel, C. D., Earl, H. D., et al. (2003). Role of white matter lesions, cerebral atrophy, and APOE on cognition in older persons with and without dementia: the Cache County, Utah, study of memory and aging. Neuropsychology, 17(3), 339-352.
Bigler, E. D., Neeley, E. S., Miller, M. J., Tate, D. F., Rice, S. A., Cleavinger, H., et al. (2004). Cerebral volume loss, cognitive deficit and neuropsychological performance: comparative measures of brain atrophy: I. Dementia. J Int Neuropsychol Soc, 10(3), 442-452.
Hulette, C. (2003). Brain Banking in the United States. Journal of Neuropahtology and Experimental Neurology, 62(7), 715-722.
 
Use of other Drugs
Carlson, M. C., Tschanz, J. T., Norton, M. C., Welsh-Bohmer, K., Martin, B. K., & Breitner, J. C. (2002). H2 histamine receptor blockade in the treatment of Alzheimer disease: a randomized, double-blind, placebo-controlled trial of nizatidine. Alzheimer Dis Assoc Disord, 16(1), 24-30.
Khachaturian, A. S., Zandi, P. P., Lyketsos, C. G., Hayden, K. M., Skoog, I., Norton, M. C., et al. (2006). Antihypertensive Medication Use and Incident Alzheimer Disease: The Cache County Study. Arch Neurol.
Zandi, P. P., Sparks, D. L., Khachaturian, A. S., Tschanz, J., Norton, M., Steinberg, M., et al. (2005). Do statins reduce risk of incident dementia and Alzheimer disease? The Cache County Study. Arch Gen Psychiatry, 62(2), 217-224.
 
Mental & Behavioral Disturbances
Leroi, I., Voulgari, A., Breitner, J. C., & Lyketsos, C. G. (2003). The epidemiology of psychosis in dementia. Am J Geriatr Psychiatry, 11(1), 83-91.;
Lyketsos, C. G., Sheppard, J. M., Steinberg, M., Tschanz, J. A., Norton, M. C., Steffens, D. C., et al. (2001). Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the Cache County study. Int J Geriatr Psychiatry, 16(11), 1043-1053.
Lyketsos, C. G., Steinberg, M., Tschanz, J. T., Norton, M. C., Steffens, D. C., & Breitner, J. C. (2000). Mental and behavioral disturbances in dementia: findings from the Cache County Study on Memory in Aging. Am J Psychiatry, 157(5), 708-714.
Onyike, C. U., Sheppard, J. M., Tschanz, J. T., Norton, M. C., Green, R. C., Steinberg, M., et al. (2007). Epidemiology of apathy in older adults: the Cache County Study. Am J Geriatr Psychiatry, 15(5), 365-375.
Steinberg, M., Corcoran, C., Tschanz, J., Huber, C., Welsh-Bohmer, K., Norton, M., et al. (2006). Risk Factors for Neuropsychiatry symptoms in dementia:  The Cache County Study. Int J Geriatr Psychiatry, 21(9), 824-830.
Steinberg, M., Sheppard, J. M., Tschanz, J. T., Norton, M. C., Steffens, D. C., Breitner, J. C., et al. (2003). The incidence of mental and behavioral disturbances in dementia: the cache county study. J Neuropsychiatry Clin Neurosci, 15(3), 340-345.
Steinberg, M., Tschanz, J. T., Corcoran, C., Steffens, D. C., Norton, M. C., Lyketsos, C. G., et al. (2004). The persistence of neuropsychiatric symptoms in dementia: the Cache County Study. Int J Geriatr Psychiatry, 19(1), 19-26.
 
Vascular Risk Factors & AD
Hayden, K. M., Pieper, C. F., Welsh-Bohmer, K. A., Breitner, J. C., Norton, M. C., & Munger, R. (2004). Self- or proxy-reported stroke and the risk of Alzheimer disease. Arch Neurol, 61(6), 982; author reply 983.
Hayden, K. M., Zandi, P. P., Lyketsos, C. G., Khachaturian, A. S., Bastian, L. A., Charoonruk, G., et al. (2006). Vascular risk factors for incident Alzheimer disease and vascular dementia: the Cache County study. Alzheimer Dis Assoc Disord, 20(2), 93-100.
Lyketsos, C. G., Toone, L., Tschanz, J., Corcoran, C., Norton, M., Zandi, P., et al. (2006). A population-based study of the association between coronary artery bypass graft surgery (CABG) and cognitive decline: the Cache County study. Int J Geriatr Psychiatry, 21(6), 509-518.
 
Other Areas of Interest
Bandeen-Roche K, L., KY. (2002). Modelling multivariate failure time associations in the presence of a competing risk. Biometrika, 89(2), 299-314.
Bastian, L. A., West, N. A., Corcoran, C., & Munger, R. G. (2005). Number of children and the risk of obesity in older women. Prev Med, 40(1), 99-104.
Hayden, K. M., Khachaturian, A. S., Tschanz, J. T., Corcoran, C., Nortond, M., & Breitner, J. C. (2003). Characteristics of a two-stage screen for incident dementia. J Clin Epidemiol, 56(11), 1038-1045.
Hayden, K. M., Warren, L. H., Pieper, C. F., Ostbye, T., Tschanz, J. T., Norton, M. C., et al. (2005). Identification of VAD and AD Prodromes: The Cache County Study. Alzheimer's & Dementia, 1(1), 19-29.
Khachaturian, A. S., Gallo, J. J., & Breitner, J. C. (2000). Performance characteristics of a two-stage dementia screen in a population sample. J Clin Epidemiol, 53(5), 531-540.
Lyketsos, C. G., Toone, L., Tschanz, J., Rabins, P. V., Steinberg, M., Onyike, C. U., et al. (2005). Population-based study of medical comorbidity in early dementia and "cognitive impairment, no dementia (CIND)": association with functional and cognitive impairment: The Cache County Study. Am J Geriatr Psychiatry, 13(8), 656-664.
Miech, R. A., Breitner, J. C., Zandi, P. P., Khachaturian, A. S., Anthony, J. C., & Mayer, L. (2002). Incidence of AD may decline in the early 90s for men, later for women: The Cache County study. Neurology, 58(2), 209-218.
Norton, M. C., Breitner, J. C., Welsh, K. A., & Wyse, B. W. (1994). Characteristics of nonresponders in a community servey of the elderly. J Am Geriatr Soc, 42(12), 1252-1256.
Norton, M. C., Tschanz, J. A., Fan, X., Plassman, B. L., Welsh-Bohmer, K. A., West, N., et al. (1999). Telephone adaptation of the Modified Mini-Mental State Exam (3MS). The Cache County Study. Neuropsychiatry Neuropsychol Behav Neurol, 12(4), 270-276.
Ostbye, T., Krause, K. M., Norton, M. C., Tschanz, J., Sanders, L., Hayden, K., et al. (2006). Ten dimensions of health and their relationships with overall self-reported health and survival in a predominately religiously active elderly population: the cache county memory study. J Am Geriatr Soc, 54(2), 199-209.
Plassman, B., Khachaturian, A., Townsend, J. J., Ball, M. J., Steffens, D. C., Leslie, C., et al. (2006). Comparison of clinical and neuropathologic diagnoses of Alzheimer's disease in 3 epidemiologic samples. Alzheimer's & Dementia, 2, 2-11.
Tschanz, J., Welsh-Bohmer, K., Lyketsos, C. G., Corcoran, C., Green, R. C., Hayden, K., et al. (2006). Conversion to dementia from mild cognitive disorder.  The Cache County Study. Neurology, 67(2), 229-234.
Tschanz, J. T., Norton, M.C., Calvert T. (2001). Need for Assistance in Daily Living Acitivities and Caregiver Stress: Results From a Commuinity Survey of Over 5,000 Individuals in Cache County, Utah. Intermountain Aging Review, 3(1), 15-17.
Tschanz, J. T., Corcoran, C., Skoog, I., Khachaturian, A. S., Herrick, J., Hayden, K. M., et al. (2004). Dementia: the leading predictor of death in a defined elderly population: the Cache County Study. Neurology, 62(7), 1156-1162.
Tschanz, J. T., Treiber, K., Norton, M. C., Welsh-Bohmer, K., Toone, L., Zandi, P., et al. (2005). A population study of Alzheimer's Disease: Findings from the Cache County Study on Memory, Health, and Aging. Care Management Journals, 6(2), 107-114.
Tschanz, J. T., Welsh-Bohmer, K. A., Plassman, B. L., Norton, M. C., Wyse, B. W., & Breitner, J. C. (2002). An adaptation of the modified mini-mental state examination: analysis of demographic influences and normative data: the cache county study. Neuropsychiatry Neuropsychol Behav Neurol, 15(1), 28-38.
Tschanz, J. T., Welsh-Bohmer, K. A., Skoog, I., West, N., Norton, M. C., Wyse, B. W., et al. (2000). Dementia diagnoses from clinical and neuropsychological data compared: the Cache County study. Neurology, 54(6), 1290-1296.
Welsh-Bohmer, K., Breitner, J. C., Hayden, K., Lyketsos, C. G., Zandi, P., Tschanz, J., et al. (2006). Modifying dementia risk and trajectories of cognitive decline in aging: The Cache County Memory Study. Alzheimer's & Dementia, 2, 257-260.