2. Sidwell, R. W., B. D. Thorpe, and L. P. Gebhardt. 1964. Studies of latent Q fever infections. II. Effects of multiple cortisone injections. Am. J. Hyg. 79:320-327.
3. Sidwell, R. W., G. J. Dixon, and S. M. Sellers. 1965. Inhibition of Friend leukemia virus by porfiromycin. In: Antimicrobial Agents and Chemotherapy (J.C. Sylvester, ed.), Amer. Soc. Microbiol., Ann Arbor, pp. 767-771.
4. Sidwell. R. W., G. J. Dixon, S. M. Sellers, and F. M. Schabel, Jr. 1965. In vivo antiviral activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Appl. Microbiol. 13:579-589.
5. Sidwell, R. W., G. J. Dixon, S. M. Sellers, C. F. Maxwell, and F. M. Schabel, Jr. 1965. Effect of host weight loss on Friend leukemia virus infections in Swiss, DBA/2 and BALB/c mice. Proc. Soc. Expt. Biol. Med. 119:141-1147.
6. Sidwell, R. W., G. J. Dixon, S. M. Sellers, M. A. Chirigos, and F. M. Schabel, Jr. 1965. Development of Friend leukemia virus in spleen and plasma of Swiss mice. Cancer Chemother. Repts. 48:5-59.
7. Sidwell, R. W., G. Arnett, and G. J. Dixon. 1966. In vitro studies on the antiviral activity of 1,3-bis(2-chloroethyl)-1-nitrosourea. Appl. Microbiol. 14:405-410.
8. Sidwell, R. W. and L. P. Gebhardt. 1966. Studies of latent Q fever infections. III. Effects of parturition upon latently infected guinea pigs and white mice. Amer. J. Epidemiol. 84:132-137.
9. Sidwell, R. W., G. J. Dixon, S. M. Sellers, and F. M. Schabel, Jr. 1966. In vivo antiviral properties of biologically active compounds. I. Studies with Friend leukemia virus. Cancer Chemother. Repts. 50:299-312.
10. Sidwell, R. W., S. M. Sellers, and G. J. Dixon. 1966. Herpes simplex keratitis in hamsters as a system for evaluating potential antiviral agents. In: Antimicrobial Agents and Chemotherapy (G. L. Hobby, ed.), Amer. Soc. Microbiol., Ann Arbor, pp. 483-488.
11. Sidwell, R. W., G. J. Dixon, and E. McNeil. 1967. Quantitative studies on fabrics as disseminators of viruses. III. Persistence of vaccinia virus on fabrics impregnated with a virucidal agent. Appl. Microbiol. 15:921-927.
12. Sidwell, R. W., S. M. Sellers, G. J. Dixon, and F. M. Schabel, Jr. 1968. Effects of a series of purine analogs in Friend leukemia virus infections in mice. Cancer Res. 28:35-40.
13. Sidwell, R. W., G. J. Dixon, S. M. Sellers, and F. M. Schabel, Jr. 1968. In vivo antiviral properties of biologically active compounds. II. Studies with influenza and vaccinia viruses. Appl. Microbiol. 16:370-392.
14. G. J. Dixon, R. W. Sidwell, F. A. Miller, and B. J. Sloan. 1969. The antiviral activity of 9-β-D-arabinofuranosyladenine (Ara-A). V. Activity against intracerebral vaccinia virus infections in mice. Antimicrob. Ag. Chemother. pp. 172-199.
15. Schardein, J. L. and R. W. Sidwell. 1969. The antiviral activity of 9-β-D-arabinofuranosyladenine (Ara-A). III. Reduction in evidence of encephalitis in treated herpes simplex infected hamsters. Antimicrob. Ag. Chemother. pp. 155-160.
16. Sidwell, R. W. and G. J. Dixon. 1969. The role of virucides in controlling virus dissemination by fabrics. Detergent Additives Symposium, American Oil Chemists’ Society annual Meeting, October 23, 1968. J. Amer. Oil Chemists’ Society 46:532-536.
17. Sidwell, R. W., G. Arnett, G. J. Dixon, and F. M. Schabel, Jr. 1969. Purine analogs as potential anticytomegalovirus agents. Proc. Soc. Expt. Biol. Med. 131:1223-1230.
18. Sidwell, R. W., G. J. Dixon, F. M. Schabel, Jr., and D. H. Kaump. 1969. The antiviral activity of 9-β-arabinofuranosyladenine (Ara-A). II. Activity against herpes simplex keratitis in hamsters. Antimicrob. Ag. Chemother. pp. 148-154.
19. Sidwell, R. W., G. J. Dixon, L. Westbrook, and E. A. Dulmadge. 1969. Procedure for the evaluation of the virucidal effectiveness of an ethylene oxide gas sterilizer. Appl. Microbiol. 17:790-769.
20. Sidwell, R. W., G. J. Dixon, P. Compton, and F. M. Schabel, Jr. 1969. The effect of treatment with a combination of 6-mercaptopurine and porfiromycin on an established Friend leukemia virus infection. Cancer Res. 29:497-502.
21. Brockman, R. W., R. W. Sidwell, G. Arnett, and S. Shaddix. 1970. Heterocyclic aldehyde thiosemicarbazones; correlation between structure, inhibition of ribonucleotide reductase and inhibition of deoxyribonucleic acid viruses. Proc. Soc. Expt. Biol. Med. 133:609-614.
22. Sidwell, R. W. 1970. Synthetic antiviral compounds. Prog. Antimicrob. Anticancer Chemother. 2:803-809.
23. Sidwell, R. W., G. Arnett, and F. M. Schabel, Jr. 1970. Effects of 9-β-D-arabinofuranosyladenine on myxoma and pseudorabies viruses. Antimicrob. Ag. Chemother. 2:44-48.
24. Sidwell, R. W., G. Arnett, and R. W. Brockman. 1970. Comparisons of the anticytomegalovirus activity of a group of pyrimidine analogs. Proc. N.Y. Acad. Sci. 173:592-602.
25. Sidwell, R. W., G. J. Dixon, and F. M. Schabel, Jr. 1970. Attempts to develop a strain of Friend leukemia virus resistant to 6-mercaptopurine or porfiromycin. Prog. Antimicrob. Anticancer Chemother. 2:26-32.
26. Sidwell, R. W., L. Westbrook, G. J. Dixon, and W. F. Happich. 1970. Potentially infectious agents associated with shearling bedpads. I. Effect of laundering with detergent-disinfectant combinations on polio and vaccinia viruses. Appl. Microbiol. 19:53-59.
27. Li, J. K.-K. and J. T. Seto. 1971. Electron microscopy study of ribonucleic acid of myxoviruses. J. Virology 7:524-530.
28. Sidwell, R. W. and J. H. Huffman. 1971. Use of disposable micro tissue culture plates for antiviral and interferon induction studies. Appl. Microbiol. 22:797-801.
29. Sidwell, R., J. Huffman, D. Shuman, K. Muneyama, and R. Robins. 1971. Cyclic AMP Derivatives as Antiviral Agents. Advances in Antimicrobial and Antineoplastic Chemotherapy, Proceedings of the VIIth International Congress of Chemotherapy, Prague. Urban & Schwarzenberg, Vienna, 1972, pp. 313-314.
30. Allen, L. B. and R. W. Sidwell. 1972. Target-organ treatment of neurotropic virus diseases: Efficacy as a chemotherapy tool and comparison of activity of 9-β-D-arabinofuranosyladenine, 1-β-D-arabinofuranosylcytosine, 5-iodo-2'-deoxyuridine, and trifluorothymidine. Antimicrob. Ag. Chemother. 2:229-233.
31. Burnham, W. S., R. W. Sidwell, R. L. Tolman, and M. G. Stout. 1972. Synthesis and antiviral activity of 4'-hydroxy-5,6,7,8-tetramethoxyflavone. J. Med. Chem. 15:1075-1076.
32. Khare, G. P., R. W. Sidwell, J. H. Huffman, R. L. Tolman, and R. K. Robins. 1972. Inhibition of RNA virus replication in vitro by 3-deazacytidine and 3-deazauridine. Proc. Soc. Expt. Biol. Med. 140:880-884.
33. Long, R. A., G. L. Szekeres, T. A. Khwaja, R. W. Sidwell, L. N. Simon, and R. K. Robins. 1972. The synthesis, antitumor and antiviral activity of 1-β-D-arabinofuranosylpurine 3',5'-cyclic phosphate. J. Med. Chem. 15:1215.
34. Sidwell, R. W., G. Arnett, and F. M. Schabel, Jr. 1972. In vitro effect of a variety of biologically active compounds on human cytomegalovirus. Chemotherapy. 17:259-282.
35. Sidwell, R. W., J. H. Huffman, G.P. Khare, L. B. Allen, J. T. Witkowski, and R. K. Robins. 1972. Broad-spectrum antiviral activity of Virazole: 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide. Science 177:705-706.
36. Smith, C. W., R. W. Sidwell, R. K. Robins, and R. L. Tolman. 1972. Azapurine nucleosides 2. The synthesis and antiviral activity of 7-amino-3-α-D-arabinofuranosyl-v-triazolo[4,5-d]pyrimidine and related nucleosides. J. Med. Chem. 15:883-887.
37. Witkowski, J. T., R. K. Robins, R. W. Sidwell, and L. N. Simon. 1972. The design, synthesis, and broad spectrum antiviral activity of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides. J. Med. Chem. 15:1150-1154.
38. Allen, L.B., J.H. Huffman, and R.W. Sidwell. 1973. Failure of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole, ICN 1229) to stimulate interferon. Antimicrob. Ag. Chemother. 3:534-535.
39. Boswell, K. H., J. P. Miller, D. A. Shuman, R. W. Sidwell, L. M. Simon, and R. K. Robins. 1973. Synthesis and biological activity of certain carbamoyl and carbomyl derivatives of adenosine 3',5'-cyclic phosphate. J. Med. Chem. 16:1075-1079.
40. Huffman, J. H., R. W. Sidwell, G. P. Khare, J. T. Witkowski, L. B. Allen, and R. K. Robins. 1973. In vitro effect of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses. Antimicrob. Ag. Chemother. 3:235-241.
41. Khare, G.P., R.W. Sidwell, J.T. Witkowski, L.B. Allen, and R.K. Robins. 1973. Suppression by 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole, ICN 1229) of influenza virus-induced infections in mice. Antimicrob. Ag. Chemother. 3:235-238.
42. Khwaja, T. A., L. Kigwana, G. Szekeres, R. A. Long, R. W. Sidwell, and R. K. Robins. 1973. N4-β-D-Ribofuranosyltriazin-3-one-N1-oxide (ICN 3520), a new uridine antagonist exhibiting antitumor activity. Proc. Amer. Assoc. Cancer Res., p. 17.
43. Sidwell, R. W., L. B. Allen, G. P. Khare, J. H. Huffman, J. T. Witkowski, L. N. Simon, and R. K. Robins. 1973. Effect of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole, ICN 1229) on herpes and vaccinia keratitis and encephalitis in laboratory animals. Antimicrob. Ag. Chemother. 3:242-246.
44. Sidwell, R. W., L. N. Simon, J. H. Huffman, L. B. Allen, R. A. Long, and R. K. Robins. 1973. DNA virus inhibitory activity of 1-β-D-arabinofuranosylcytosine-3',5'-cyclic phosphate. Nature, New Biol. 242:204-206.
45. Sidwell, R.W., L.B. Allen, J.H. Huffman, T.A. Khwaja, R.L. Tolman, and R.K. Robins. 1973. Anti-DNA virus activity of the 5'-nucleotide and 3',5'-cyclic nucleotide of 9-β-D-arabinofuranosyladenine. Chemotherapy 19:325-340.
46. Simon, L. N., R. W. Sidwell, G. P. Khare, D. G. Streeter, J. P. Miller, J. T. Witkowski, J. H. Huffman, and R. K. Robins. 1973. Molecular basis of antiviral chemotherapy: Virazole, a new broad spectrum antiviral agent. In: Virus Research (C.F. Fox and W. S. Robinson, eds.), pp. 415-436.
47. Streeter, D. G., J. T. Witkowski, G. P. Khare, R. W. Sidwell, R. J. Bauer, R. K. Robins, and L. N. Simon. 1973. Mechanism of action of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent. Proc. Nat. Acad. Sci. USA 70:1174-1178.
48. Witkowski, J. T., R. K. Robins, G. P. Khare, and R. W. Sidwell. 1973. Synthesis and antiviral activity of 1,2,4-triazole-3-thiocarboxamide and 1,2,4-triazole-3-carboxamidine ribonucleosides. J. Med. Chem. 16:935-937.
49. Allen, L.B., N.C. Eagle, J.H. Huffman, D.A. Shuman, R.B. Meyer, and R.W. Sidwell. 1974. Enhancement of interferon action in L-cells by cyclic nucleotides. Proc. Soc. Expt. Biol. Med. 146:580-584.
50. Mian, A. M., R. Harris, R. W. Sidwell, R. K. Robins, and T. A. Khwaja. 1974. The synthesis and biological activity of 9-β-D-arabinofuranosyladenine-3’5'-cyclic phosphate and 9-β-D-arabinofuranosylguanine-3',5'-cyclic phosphate. J. Med. Chem. 17:259-262.
51. Miyai, K., L. B. Allen, J. H. Huffman, R. W. Sidwell, and R. L. Tolman. 1974. Synthesis and biological activity of 9-β-D-arabinofuranosyl-2-substituted adenine derivatives. J. Med. Chem. 17:242-244.
52. Sidwell, R. W., L. N. Simon, J. T. Witkowski, and R. K. Robins. 1974. Antiviral activity of Virazole: Review and structure-activity relationships. Proc. 8th Intl. Cong. Chemother., Athens, Greece. Prog. in Chemother. 2:889-903.
53. Sidwell, R.W., J.H. Huffman, L.B. Allen, R.B. Meyer, Jr., D.A. Shuman, L.N. Simon, and R. K. Robins. 1974. In vitro antiviral activity of 6-substituted 9-β-D-ribofuranosylpurine 3',5'-cyclic phosphates. Antimicrob. Ag. Chemother. 5:652-657.
54. Allen, L. B., J. H. Huffman, G. R. Revankar, R. L. Tolman, L. N. Simon, R. K. Robins, and R. W. Sidwell. 1975. Efficacy of 9-β-D-ribofuranosylhypoxanthine 5'-phosphate in therapy of equine abortion virus-induced hepatitis in hamsters. Antimicrob. Ag. Chemother. 8:468-473.
55. Allen, L. B., J. M. Thompson, J. H. Huffman, G. R. Revankar, R. L. Tolman, L. N. Simon, R. K. Robins, and R. W. Sidwell. 1975. Inhibition of experimental deoxyribonucleic acid virus-induced encephalitis by 9-β-D-ribofuranosylhypoxanthine 5'-phosphate. Antimicrob. Ag. Chemother. 8:474-478.
56. Cook, P. D., R. J. Rousseau, A. M. Mian, R. B. Meyer, Jr., P. Dea, G. Ivanovics, D. G. Streeter, J. T. Witkowski, M. G. Stout, L. N. Simon, R. W. Sidwell, and R. K. Robins. 1975. A new class of potent guanine antimetabolites. Synthesis of 3-deazaguanine, 3-deazaguanosine, and 3-deazaguanylic acid by a novel ring closure of imidazole precursors. Amer. Chem. Soc. 97:2916-2917.
57. Revankar, G. R., J. H. Huffman, L. B. Allen, R. W. Sidwell, R. K. Robins, and R. L. Tolman. 1975. Synthesis and antiviral activity of certain 5'-monophosphates of 9-β-D-arabinofuranosyladenine and 9-β-D-arabinofuranosylhypoxanthine. J. Med. Chem. 18:721-726.
58. Sidwell, R. W., L. B. Allen, J. H. Huffman, G. R. Revankar, R. K. Robins, and R. L. Tolman. 1975. Viral keratitis-inhibitory effect of 9-β-D-arabinofuranosylhypoxanthine 5'-phosphate. Antimicrob. Ag. Chemother. 8:463-467.
59. Sidwell, R. W., L. B. Allen, J. H. Huffman, J. T. Witkowski, and L. N. Simon. 1975. Effect of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Ribavirin) on Friend leukemia virus infections in mice. Proc. Soc. Expt. Biol. Med. 148:854-858.
60. Sidwell, R.W., G.P. Khare, L.B. Allen, J.H. Huffman, J.T. Witkowski, L.N. Simon, and R.K. Robins. 1975. In vitro and in vivo effect of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Ribavirin) on types 1 and 3 parainfluenza virus infections. Chemotherapy 21:205-220.
61. Allen, L. B., C. Hintz, S. M. Wolf, J. H. Huffman, L. N. Simon, R. K. Robins, and R. W. Sidwell. 1976. Effect of 9-β-D-arabinofuranosylhypoxanthine 5'-phosphate (ara-HxMP, ICN 3952) on type 2 herpesvirus hominus (HVH/2)-induced genital lesions and encephalitis in female mice. J. Infect. Dis. 133:A178-A183.
62. Sidwell, R. W. 1976. Viral diseases: A review of chemotherapy systems. In: Chemotherapy of Infectious Disease (H. Gadebusch, ed.), CRC Press, Cleveland. pp. 31-54.
63. Sidwell, R. W., L. B. Allen, J. H. Huffman, J. T. Witkowski, P. D. Cook, R. L. Tolman, G. R. Revankar, L. N. Simon, and R. K. Robins. 1976. The potential of nucleosides as antiviral agents. Proc. 9th Intl. Cong. Chemother., London, England, Chemotherapy 6:279-294.
64. Srivastava, P. C., T. R. Matthews, L. B. Allen, R. W. Sidwell, and R. K. Robins. 1976. Synthesis, antiviral and antimicrobial activity of certain 1-β-D-ribofuranosyl-4,5-disubstituted imidazoles. J. Med. Chem. 19:1020-1026.
65. Allen, L. B., J. H. Huffman, P. D. Cook, R. B. Meyer, Jr., R. K. Robins, and R. W. Sidwell. 1977. Antiviral activity of 3-deazaguanine, 3-deazaguanosine and 3-deazaguanylic acid. Antimicrob. Ag. Chemother. 12:114-119.
66. Allen, L. B., S. M. Wolf, C. J. Hintz, J. H. Huffman, and R. W. Sidwell. 1977. Effect of ribavirin on type 2 Herpesvirus hominus in vitro and in vivo. Ann. N.Y. Acad. Sci. 284:247-253.
67. Ellenhorn, M. J., R. W. Sidwell, J. M. Lima, R. A. Long, L. B. Allen, and H. Fernandez-Zertuche. 1977. Ribavirin (Virazole): Review of clinical efficacy in human viral infection. Current Chemotherapy, pp. 1027-1029. Amer. Soc. Microbiol., Washington, D.C.
68. Huffman, J. H., L. B. Allen, and R. W. Sidwell. 1977. Comparison of development of resistant strains of type 1 herpes simplex virus to the in vitro antiviral activity of iododeoxyuridine or ribavirin. Ann. N.Y. Acad. Sci. 284:233-238.
69. Huffman, J. H., M. A. Anderson, L. B. Allen, and R. W. Sidwell. 1977. Lack of suppression of resistance factors to influenza infections in mice pretreated with Virazole. J. Antimicrob. Chemother. 3:79-85.
70. Revankar, G. R., J. H. Huffman, R. W. Sidwell, R. L. Tolman, R. K. Robins, and L. B. Allen. 1977. Synthesis and anti-DNA virus activity of the 5'-monophosphate and the cyclic 3',5'-monophosphate of 9-(β-D-xylofuranosyl)guanine. J. Med. Chem. 19:1026-1028.
71. Sidwell, R. W. 1977. Ribavirin: A broad spectrum antiviral having clinical usefulness. In: New Trends in Microbiology, Proc. 1976 Congress Yugoslave Microbiologists, Bled, Yugoslavia, M. Likar (ed.), Feb. 1977, pp. 367-400.
72. Sidwell, R. W., J. H. Huffman, N. Campbell, and L. B. Allen. 1977. Effect of ribavirin on viral hepatitis in laboratory animals. Ann. N.Y. Acad. Sci. 284:239-246.
73. Sidwell, R. W., M. H. Ellenhorn, I. W. Hillyard and J. M. Lima. 1977. Safety evaluations of the broad-spectrum antiviral agent ribavirin (Virazole). Current Chemotherapy, pp. 335-338. Amer. Soc. Microbiol., Washington, D.C.
74. Srivastava, P. C., M. V. Pickering, L. B. Allen, D. G. Streeter, M. T. Campbell, J. T. Witkowski, R. W. Sidwell, and R. K. Robins. 1977. Synthesis and antiviral activity of certain thiazole C-nucleosides. J. Med. Chem. 20:256-262.
75. Allen, L. B., K. H. Boswell, T. A. Khwaja, R. B. Meyer, R. W. Sidwell, J. T. Witkowski, L. F. Christensen, and R. K. Robins. 1978. Synthesis and antiviral activity of some phosphates of the broad spectrum antiviral nucleoside, 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide, ribavirin. J. Med. Chem. 21:742-746.
76. Cook, P. D., L. B. Allen, D. G. Streeter, J. H. Huffman, and R. W. Sidwell. 1978. Synthesis, antiviral and enzymatic studies of certain 3-deazaguanines and their imidazolecarboxamide precursors. J. Med. Chem. 21:1212-1217.
77. Sidwell, R. W. 1978. Current status of the antiviral drug, ribavirin. Repts. VII Intl. Cong. of Infec. Parasitic Dis. (Bulgarian Acad. Sci, Varna) 1:638-647.
78. Sidwell, R. W. 1978. Significant antiviral substances: An overview. Repts. VII Intl. Cong. of Infec. Parasitic Dis. (Bulgarian Acad. Sci., Varna) 1:626-637.
79. Mian, A. M., R. A. Long, L. B. Allen, R. W. Sidwell, R. K. Robins, and T. A. Khwaja. 1979. Synthesis and antitumor and antiviral activities of 1-β-D-arabinofuranosyl-2-amino-1,4(2H)-iminopyrimidine and its derivatives. J. Med. Chem. 22:514-518.
80. Sidwell, R. W. 1979. Test systems for evaluating the antiviral activity of nucleoside analogues. Proc. NATO Adv. Study Inst. Nucleoside Analogues: Chem., Biol., and Med. Appl. (R. T. Walker, E. DeClercq and F. Eckstein, eds.), Plenum, NY, pp. 337-362.
81. Sidwell, R. W. and J. T. Witkowski. 1979. Antiviral Agents. In: Burger’s Medicinal Chemistry, Pt. II, Wiley, N.Y. pp. 543-593.
82. Sidwell, R. W., R. K. Robins, and I. W. Hillyard. 1979. Ribavirin: An antiviral agent. Pharmacol. Therapeutics 6:123-146.
83. Drach, J. C. and R. W. Sidwell. 1980. Antiviral agents. Ann. Rept. Med. Chem. 15:149-161.
84. Li, J. K.-K., J. C. Keene, P. P. Scheible, and W. K. Joklik. 1980. Nature of the 3’-terminal sequences of the plus and minus strands of the S1 gene of reovirus serotypes 1, 2 and 3. Virology 105:41-51.
85. Li, J. K.-K., P. P. Scheible, J. D. Keene, and W. K. Joklik. 1980. Evidence that the plus strand of reovirus gene S2 is identical with its in virtro transcript. Virology 105:282-286.
86. Li, J. K.-K., T. Miyakawa, and C. F. Fox. 1980. Protein organization in Newcastle disease virus as revealed by perturbant treatment. J. Virology 34:268-271.
87. Sidwell, R. W. 1980. Ribavirin: In vitro antiviral activity. In: Ribavirin: A Broad Spectrum Antiviral Agent. Academic, N.Y. pp. 23-42.
88. Sidwell, R. W. and R. K. Olsen. 1980. 5-Membered azaheterocycles and their nucleosides. In: Virus Chemotherapy (F. Hahn, ed.), Karger, Basel, pp. 208-232.
89. Smith, R. A., R. W. Sidwell, and R. K. Robins. 1980. Antiviral mechanisms of action. Ann. Rev. Pharmacol. Toxicol. 20:259-284.
90. Li, J. K.-K., J. D. Keene, P. P. Scheible, and W. K. Joklik. 1981. Terminal sequence homologies in reovirus genes. P. 129-143. In: Bernard Fields, Rudolf Jaenisch and C. Fred Fox, (eds.), Animal Virus Genetics (ICN-UCLA Symposia on Mollecular and Cellular Biology VXIII), Academic Press, New York, N.Y.
91. Sidwell, R. W. and D. F. Smee. 1981. Bovine leukemia virus inhibition in vitro by ribavirin. Antiviral Res. 1:47-54.
92. Smee, D. F., R. W. Sidwell, B. B. Barnett, and R. S. Spendlove. 1981. A bioassay system for determining ribavirin levels in human serum and urine. Chemotherapy 27:1-11.
93. Smee, D. F., R. W. Sidwell, B. B. Barnett, and R. S. Spendlove. 1981. Inhibition of rotaviruses by selected antiviral substances. Proc. Intl. Conf. on Neonatal Diarrhea Vet. Inf. Dis. Org., Saksatoon, pp. 123-136.
94. Smee, D. F., R. W. Sidwell, B. B. Barnett, R. S. Spendlove, and R. P. Sharma. 1981. Development of antiviral levels of ribavirin in serum and urine of orally treated rats. Chemotherapy 27:12-17.
95. Smee, D. F., R. W. Sidwell, S. M. Clark, B. B. Barnett, and R. S. Spendlove. 1981. Inhibition of bluetongue and Colorado tick fever orbiviruses by selected antiviral substances. Antimicrob. Ag. Chemother. 20:533-538.
96. Smee, D. F., R. W. Sidwell, S. M. Clark, B. B. Barnett, and R. S. Spendlove. 1981. Inhibition of reoviruses in vitro by selected antiviral substances. Antiviral Res. 1:315-323.
97. Smee, D. F., R. W. Sidwell, S. M. Clark, B. B. Barnett, and R. S. Spendlove. 1982. Inhibition of rotaviruses by selected antiviral substances: Mechanisms of viral inhibition and in vivo activity. Antimicrob. Ag. Chemother. 21:66-73.
98. Nobel, R. N., R. W. Sidwell, A. W. Mahoney, B. B. Barnett, and R. S. Spendlove. 1983. Influence of malnutrition and alterations in dietary protein on rotaviral disease. Proc. Soc. Expt. Biol. Med. 173:417-426.
99. Morrey, J. D., R. W. Sidwell, B. B. Barnett, and A. W. Mahoney. 1984. Effects of folic acid malnutrition on rotaviral infection in mice. Proc. Soc. Expt. Biol. Med. 176:77-83.
100. Huffman, J. H., E. Call, H. Alaghamandan, and R. W. Sidwell. 1985. Use of a persisting type 1 herpesvirus-induced cutaneous infection in nude mice for evaluation of antiviral substances. In: Recent Advances in Chemotherapy (J. Ishigami, ed.) pp. 1977-1978. Univ. Tokyo Press, Tokyo.
101. Sidwell, R. W. 1985. Determination of antiviral activity. In: Modern Analysis of Antibiotics (A. Aszalos, ed.), Marcel Dekker, pp. 433-480.
102. Sidwell, R. W. 1985. In vitro and in vivo inhibition of DNA viruses by ribavirin. In: Clinical Utilization of Ribavirin (R. A. Smith, ed.), Academic, N. Y., pp. 19-32.
103. Sidwell, R. W., B. B. Barnett, and A. W. Mahoney. 1985. The malnutrition/diarrhea connection. Utah Sci. 45:104-109.
104. Sidwell, R.W., G.R. Revankar, and R.K. Robins. 1985. Ribavirin: Review of a broad-spectrum antiviral agent. In: International Encyclopedia of Pharmacology and Therapeutics (D. Shugar, ed.), Pergamon Press, pp. 49-107.
105. Sidwell, R.W., J.H. Huffman, E.W. Call, H. Alaghamandan, P.D. Cook, and R.K. Robins. 1985. Activity of selenazofurin against influenza A and B viruses in vitro. Antimicrob. Ag. Chemother. 28:375-377.
106. Sidwell, R.W., J.H. Huffman, E.W. Call, H. Alaghamandan, P.D. Cook, and R.K. Robins. 1985. Effect of selenazofurin on influenza A and B virus infections in mice. Antiviral Res. 6:343-353.
107. Sidwell, R. W. 1986. Chemotherapy of veterinary viral diseases. Utah Sci. 47:100-106.
108. Sidwell, R.W. 1986. Overview of viral agents in pediatric enteric infection. Amer. J. Pediat. Dis. 5:44-45.
109. Li, J. K.-K. 1987. Chromatographic purification and immunological analysis of viral polypeptides of Mouse Mammary Tumor Viruses. J. Virol. Methods 17:299-310.
110. Li, J. K.-K., B. Parker, and T. F. Kowalik. 1987. Rapid, alkaline blot-transfer of viral ds-RNA. Anal. Biochem. 163:210-218.
111. Sidwell, R. W., J. H. Huffman, E. W. Call, R. P. Warren, L. A. Radov, and R. J. Murray. 1987. Inhibition of murine hepatitis virus infections by the immunomodulator 2,3,5,6,7,8-hexahydro-2-phenyl-8,8-dimethoxyimidazol-[1,2a]pyridine (PR879-317A). Antimicrob. Ag. Chemother. 31:1130-1134.
112. Sidwell, R.W., J.H. Huffman, E.W. Call, H. Alaghamandan, and G.J. Dixon. 1987. Effect of vidarabine in DMSO vehicle on type 1 herpesvirus-induced cutaneous lesions in laboratory animals. Chemotherapy 33:141-150.
113. Warren, R.P., M.C. Healey, A.V. Johnston, R.W. Sidwell, L.A. Radov, R.J. Murray, and C.R. Kinsolving. 1987. PR 879-317A enhances in vitro immune activity of peripheral blood mononuclear cells from patients with Down Syndrome. Intl. J. Immunopharmacol. 9:919-926.
114. Burns, N. J., B. B. Barnett, J. H. Huffman, M. I. Dawson, R. W. Sidwell, E. DeClercq and M. Kende. 1988. A newly developed immunofluorescent assay for determining the Pichinde virus-inhibitory effects of selected nucleoside analogues. Antiviral Res. 10:89-98.
115. Gabrielsen, B. J., M. A. Ussery, P. G. Canonico, G. R. Pettit, E. M. Schubert, and R. W. Sidwell. 1988. Anti-RNA-viral activities of phenanthridones related to narciclasine. Antiviral Res. 9:97.
116. Huffman, J. H., R. W. Sidwell, T. W. Schafer, and C. Shipman, Jr. 1988. Effect of 2-acetylpyridine thiosemicarbazones on in vivo type 2 herpesvirus infections. Antiviral Res. 9:140.
117. Pifat, D. Y., R. W. Sidwell, and P. G. Canonico. 1988. Toxicity evaluations of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride in rhesus monkeys: Comparison with ribavirin. Antiviral Res. 9:136.
118. Sidwell, R. W., J. H. Huffman, B. B. Barnett, and D. Y. Pifat. 1988. In vitro and in vivo Phlebovirus inhibition by ribavirin. Antimicrob. Ag. Chemother. 32:331-336.
119. Sidwell, R. W., J. H. Huffman, B. B. Barnett, M. Kende, and D. Y. Pifat. 1988. Effects of a series of immunomodulators on experimental Phlebovirus infections. Antiviral Res. 9:125.
120. Sidwell, R. W., J. H. Huffman, D. L. Barnard, and D. Y. Pifat. 1988. Effects of ribamidine, a 3-carboxamidine derivative of ribavirin, on experimentally induced Phlebovirus infections. Antiviral Res. 10:193-208.
121. Barnard, D. L., J. H. Huffman, J. L. B. Morris, R. W. Sidwell, and E. J. Reist. 1989. The effects of a human cytomegalovirus inhibitory agent, 9-(3'-phosphono-1'-hydroxymethyl-1'-propyloxymethyl)guanine, on macromolecular synthesis and in vitro antiviral activity in human diploid cells. The Pharmacologist 31:166.
122. Huffman, J. H., R. W. Sidwell, R. K. Robins, G. R. Revankar, and D. Y. Pifat. 1989. In vitro and in vivo Phlebovirus inhibition by nucleosides related to ribavirin. Nucleotides and Nucleosides 8:1159-1160.
123. Li, J. K.-K., T. Johnson, Y.-Y. Yang, and V. Shore. 1989. Selective separation of Bluetongue viral proteins and genomic ds-RNA by SDS/KCl precipitation. J. Virol. Methods 26:3-16.
124. Reist, E. J., P. A. Sturm, R. V. Pong, and R. W. Sidwell. 1989. Synthesis of phosphonic acid analogs of acyclovir and ganciclovir. Nucleotides and Nucleosides 8:919-922.
125. Reist, E.J., P.A. Sturm, R.Y. Pong, M.J. Tanga, and R.W. Sidwell. 1989. Synthesis of acyclonucleoside phosphonates for evaluation as antiviral agents. In: Nucleotide Analogues as Antiviral Agents (J. C. Martin, ed.) ACS Sympos. series 401. American Chemical Society, Washington, D.C. pp. 17-34.
126. Sidwell, R. W., J. H. Huffman, D. L. Barnard, and E. J. Reist. 1989. Effect of phosphonic acid analogs of acyclovir and ganciclovir on in vitro cytomegalovirus infections. Nucleotides and Nucleosides 8:833-836.
127. Warren, R. P., J. D. Morrey, R. A. Burger, K. M. Okleberry, and R. W. Sidwell. 1989. Murine retroviral disease enhancing effects of a pyrimidinone immunomodulator. The Pharmacologist 31:166.
128. Hwang, G.-Y., J. K.-K. Li, J.-F. Chiou, and R.-S. Tan. 1990. Chromatographic purification and characterization of EBV DNase from chemically-induced lymphoid cells. Virology 175:313-318.
129. Kowalik, T. F., Y.-Y. Yang, and J. K.-K. Li. 1990. Mollecular Cloning and comparative sequence analyses of Bluetongue virus S1 segments by selective synthesis of specific full-length DNA copies of ds-RNA genes. Virology 177:820-823.
130. Li, J. K.-K. and Y.-Y. Yang. 1990. Mapping of two immunodominant antigenic epitopes conserved among the major inner capsid protein, VP7 of five Bluetongue viruses. Virology 178:552-559.
131. Li, J. K.-K. T. F. Kowalik, R. Chuang, B. Osburn, and R. Doi. 1990. The complete nucleotide and deduced amino acid sequence of the gene encoding the major inner capsid protein, VP7, of U.S. prototype bluetongue virus serotype 17. Nucleic Acids Research 18:5302.
132. Morrey, J. D., R. P. Warren, K. M. Okleberry, R. A. Burger, M. Chirigos, and R. W. Sidwell. 1990. Effect of Imexon on Friend virus complex infection in Rfv-3r/s genotype-containing mice as a model for AIDS. Ann. N.Y. Acad. Sci. 616:575-578.
133. Morrey, J. M., R. P. Warren, K. M. Okleberry, R. A. Burger, M. I. Dawson, and R. W. Sidwell. 1990. A mouse genetics model for evaluation of biological response modifiers for the treatment of retroviral infection. J. Cell. Biochem. 140:68.
134. Morrey, J.D., R.P. Warren, K.M. Okleberry, R.A. Burger, M.I. Johnston, and R.W. Sidwell. 1990. Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection. J. Acq. Imm. Def. Synd. 3:500-510.
135. Sidwell, R. W., J. H. Huffman, J. Coombs, H. Renis, J. Huggins, and M. Kende. 1990. A comparison of pyrimidinone analog immunomodulators for treatment of Phlebovirus infections in mice. Antiviral Chem. and Chemother. 1:241-248.
136. Sidwell, R. W., J. H. Huffman, V. K. Singh, R. P. Warren, J. Coombs, R. Burger, M. Kende, and J. H. Huggins. 1990. Use of the Punta Toro virus murine phlebovirus model for the evaluation of immunomodulating agents alone and in combination with antivirals. J. Cell. Biochem. 140:71.
137. Sidwell, R.W. 1990. In vivo antiviral experiences with combinations of immunomodulators and antiviral agents. In: Recent Advances in Chemotherapy (E. Rubinstein and D. Adam, eds.) pp. 713. Lewin-Epstein, LTD, Jerusalem.
138. Sidwell, R.W., J.H. Huffman, T.W. Schafer, and C. Shipman. 1990. Influence of vehicle on topical efficacy of 2-acetylpyridine thiosemicarbazone and related derivatives on in vivo type 2 herpes simplex virus infections. Chemotherapy 36:58-69.
139. Smee, D. F., J. H. Huffman, L. L. Hall, J. W. Huggins, and R. W. Sidwell. 1990. Inhibition of Phlebovirus infections in vivo by tiazofurin and selenazofurin. Antiviral Chem. Chemother. 1:211-216.
140. Warren, R. P., R. W. Sidwell, J. H. Huffman, E. W. Call, M. C. Healey. A. V. Johnson, L. A. Radov, R. J. Murray, and C. R. Kinsolving. 1990. Effect of oxamisole on immune parameters of mice infected with murine hepatitis. Int’l J. Immunopharmacol. 12:625-630.
141. Wood, S., J. Huffman, N. Weber, D. Anderson, J. North, B. Murray, R. Sidwell, and B. Hughes. 1990. Antiviral activity of naturally occurring anthraquinones and anthraquinone derivatives. In: Biology and Chemistry of Active Natural Substances. Rheinische Friedrich-Wilhelms Universität, Bonn. pp. 166-167.
142. Barnett, B. B., N. J. Burns, K. J. Park, M. I. Dawson, M. Kende, and R. W. Sidwell. 1991. Antiviral immunotoxins: Antibody-mediated delivery of gelonin inhibits Pichinde virus replication in vitro. Antiviral Res. 15:125-138.
143. Bhagrath, M., R. Sidwell, K. Czako, K. Seyda, W. Anderson, N. Bodor, and M.E. Brewster. 1991. Improved delivery through biological membranes. 54. Synthesis, characterization and antiviral activity of a series of ribavirin chemical delivery systems: 5' and carboxamide derivatives. Antiviral Chem. & Chemother. 2:265-286.
144. Deyrup, M., R. Sidwell, R. Little, P. Druzgala, N. Bodor, and M.E. Brewster. 1991. Improved delivery through biological membranes. Synthesis and antiviral activity of a series of ribavirin chemical delivery systems: 2' and 3' derivatives. Antiviral Chem. & Chemother. 2:337-356.
145. Kowalik, T. F., and J. K.-K. Li. 1991. Bluetongue virus evolution: Sequence analysis of genomic segment S1 and major core protein VP7. Virology 81:749-755.
146. Mead, J.R., R.A. Burger, L.J. Yonk, J. Coombs, R.P. Warren, M. Kende, J. Huggins, and R.W. Sidwell. 1991. Effect of human, recombinant interleukin 2 on Punta Toro virus infections in C57BL/6 mice. Antiviral Res. 15:331-340.
147. Morrey, J. D., K. M. Okleberry, and R. W. Sidwell. 1991. Early-initiated AZT therapy prevents disease but not low levels of persistent retrovirus in mice. J. Acquired Imm. Def. Synd. 4:506-512.
148. Morrey, J. D., R. P. Warren, K. M. Okleberry, R. A. Burger, M. A. Chirigos, and R. W. Sidwell. 1991. Effect of imexon treatment on Friend virus infection using genetically defined mice as a model for HIV-1 infection. Antiviral Res. 15:51-66.
149. Morrey, J.D., S.M. Bourn, T.D. Bunch, M.K. Jackson, R.W. Sidwell, L.R. Barrows, R.A. Daynes, and C.A. Rosen. 1991. In vivo activation of human immunodeficiency virus type 1 long terminal repeat by UV type A (UV-A) light plus psoralen and UV-B light in the skin of transgenic mice. J. Virol. 65:5045-51.
150. Morrey, J.D., S.M. Bourn, T.D. Bunch, R.W. Sidwell, LR. Barrows, R.A. Daynes, and C.A. Rosen. 1991. In vivo regulation of HIV-1 long terminal repeat by UV light and various skin applicants in transgenic mice. J. AIDS 4:328.
151. Smee, D. F., J. H. Huffman, J. Coombs, J. W. Huggins, and R. W. Sidwell. 1991. Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice. Antiviral Res. 15:229-240.
152. Smee, D.F., H.A. Alaghamandan, J.H. Huffman, J. Coombs, J.W. Huggins, and R.W. Sidwell. 1991. Combination chemotherapy of Punta Toro virus infections in mice using ribavirin and 7-thia-8-oxoguanosine. Antiviral Chem. & Chemother. 2:93-97
153. Smee, D.F., R.A. Burger, J. Coombs, J.H. Huffman, and R.W. Sidwell. 1991. Progressive murine cytomegalovirus disease after termination of ganciclovir therapy in mice immunosuppressed by cyclophosphamide treatment. J. Infect. Dis. 164:958-61.
154. Barnard, D.L., J.H. Huffman, J.L.B. Morris, S.G. Wood, B.G. Hughes, and R.W. Sidwell. 1992. Evaluation of the antiviral activity and mode of action of anthraquinones, anthrones, and anthraquinone derivatives against human cytomegalovirus. Recent Adv. Chemother. 2:1772-1773.
155. Barnard, D.L., J.H. Huffman, J.L.B. Morris, S.G. Wood, B.G. Hughes, and R.W. Sidwell. 1992. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus. Antiviral Res. 17:63-77.
156. Brewster, M., R. Sidwell, M. Deyrup, and N. Bodor. 1992. Brain-enhanced delivery of ribavirin through use of redox targeting. Recent Adv. Chemother. 1:1342-1343.
157. Gabrielsen, B.J., M.J. Phelan, L. Barthel-Rosa, C.See, J.W. Huggins, D.F. Kefauver, T.P. Monath, M.A. Ussery, G.N. Chmurny, E.M. Schubert, K. Upadhya, C. Kwong, D.A. Carter, J.A. Secrist III, J.J. Kirsi, W.M. Shannon, R.W. Sidwell, G.D. Kini, and R.K. Robins. 1992. Synthesis and antiviral evaluation of N-carboxamidine-substituted analogues of 1-β-D-ribofuranosyl-1,2,4-triazole-3-carboxamide hydrochloride. J. Med. Chem. 35:3231-3238.
158. Huismans, H., B. Eaton, A. Gould, W. Laegreid, J. K.-K. Li, P. Loudon, P. Mertens, P. Roy, J. Stott, A. van Dijk, and A. Wade-Evans. 1992. WHO Working Team Report on Molecular Virology: Identify nucleic acid sequences and antigens/epitopes for use in diagnostics procedures and molecular epidemiology. In: Walton, T. E. and Osburn, B. I. (eds.), Bluetongue, African Horse Sickness and Related Orbiviruses. pp. 982-989, CRC Press, Boca Raton, Florida.
159. Hwang, G.-Y., Y.-Y. Yang, J.-F. Chiou, and J. K.-K. Li. 1992. Comparative sequence analyses of the cognate structural protein VP6 genes of five US Bluetongue Viruses. Virus Research 24:315-323.
160. Hwang, G.-Y., Y.-Y. Yang, J.-F. Chiou, and J. K.-K. Li. 1992. Sequence conservation among the cognate nonstructural Ns3/3A protein genes of six bluetongue viruses. Virus Research 23:151-161.
161. Li, J. K.-K., and G.-Y. Hwang. 1992. Identification of a serotypic neutralization epitope unique to VP2 of bluetongue virus 13. In: Walton, T. E. and Osburn, B. I. (eds.), Bluetongue, African Horse Sickness and Related Orbiviruses. pp. 439-443, CRC Press, Boca Raton, Florida.
162. Li, J. K.-K., and Y.-Y. Yang. 1992. Biochemical and immunological characterization of VP5 of five US bluetongue virus. In: Walton, T. E., and Osburn, B. I., (eds.), Bluetongue, African Horse Sickness and Related Orbiviruses. pp. 433-438, CRC Press, Boca Raton, Florida.
163. Morrey, J.D., J.R. Mead, R.P. Warren, K.M. Okleberry, R.A. Burger, and R.W. Sidwell. 1992. Elucidation of mode of retroviral-inhibitory effects of imexon through use of immune competent and severe combined immune deficiency (SCID) mice. Antiviral Res. 17:223-233.
164. Morrey, J.D., T.D. Bunch, R.W. Sidwell, L.R. Barrows, R.A. Dayms, and C.A. Rosen. 1992. HIV-1 LTR activation model: Evaluation of various agents in skin of transgenic mice. J. AIDS 5:1195-1203.
165. Sidwell, R., J. Huffman, J. Gilbert, B. Moscon, G. Pedersen, R. Burger, and R. Warren. 1992. Utilization of pulse oximetry for the study of the inhibitory effects of antiviral agents on influenza virus in mice. Antimicrob. Ag. Chemother. 36:473-476.
166. Sidwell, R.W., J. H. Huffman, D.F. Smee, J. Gilbert, M. Kende, and J. Huggins. 1992. Biological response modifiers in combination with antivirals against experimentally-induced virus infections. Canad. J. Inf. Dis. 3(supp. B):49-54.
167. Sidwell, R.W., J.H. Huffman, D.F. Smee, J. Gilbert, A. Gessaman, A. Pease, R.P. Warren, J. Huggins, and M. Kende. 1992. Potential role of immunomodulators for treatment of Phlebovirus infections of animals. N.Y. Acad. Sci. 653:344-355.
168. Sidwell, R.W., K. Okleberry, R.P. Warren, R. Burger, J. Mead, and J.D. Morrey. 1992. Experiences with biological response modifiers in animal models for AIDS. Recent Adv. Chemother. 1:934-935.
169. Sidwell, R.W., M. Hitchcock, K.M. Okleberry, R.A. Burger, R.P. Warren, and J.D. Morrey. 1992. Suppression of murine retroviral disease by 2',3'-didehydro-2',3'-dideoxythymidine (D4T). Antiviral Res. 19:313-324.
170. Smee, D.F., A. Pease, R.A. Burger, J.H. Huffman, J.D. Morrey, K.M. Okleberry, R.L. Noble, and R.W. Sidwell. 1992. Ganciclovir treatment of murine cytomegalovirus infection in mice immunosuppressed by prior infection with Friend leukemia virus. Antiviral Chem. & Chemother. 3:327-333.
171. Smee, D.F., H.B. Cottam, B.S. Sharma, G.D. Kini, G.R. Revankar, E.A. Ojo-Amaize, R.W. Sidwell, W.B. Jolley, and R.K. Robins. 1992. Antiviral and immunoenhancing properties of 7-thia-8-oxoguanosine and related guanosine analogs. Canad. J. Inf. Dis. 3(Suppl. B):41-48.
172. Smee, D.F., J.L.B. Morris, J.A. Leonhardt, J.R. Mead, A. Holy, and R.W. Sidwell. 1992. Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine. Antimicrob. Ag. Chemother. 36:1837-1842.
173. Warren, R. P., R. A. Burger, R. W. Sidwell, and L. L. Clark. 1992. Effect of triacontanol on numbers and functions of cells involved in inflammatory responses. Proc. Soc. Exp. Biol. Med. 200:349-352.
174. Warren, R.P., J.D. Morrey, R.A. Burger, K.M. Okleberry, and R.W. Sidwell. 1992. Murine retroviral disease-enhancing effects of a pyrimidinone immunomodulator. Antiviral Res. 19:233-245.
175. Yang, Y.-Y., and J. K.-K. Li. 1992. Complete genomic sequences of the GP5 protein gene ov bluetongue virus serotype 11 and 17. Virus Research 23, 163-171.
176. Yang, Y.-Y., G.-Y. Hwang, J.-F. Chiou, I. J. Huang, and J. K.-K. Li. 1992. Evolutionary analysis of five US Bluetongue viruses using the cognate S2 genes. Virus Research 25:241-249.
177. Yang, Y.-Y., J. K.-K. Li, T. M. Johnson, J. O. Mecham, and J. P. Tam. 1992. Epitopic mapping of the immunodominant linear and conformation-dependent antigenic determinations on the major outer capsid protein, GP5, of five US bluetongue viruses. Virology 188, 530-536.
178. Barnard, D.L., D.F. Smee, J.H. Huffman, L.R. Meyerson, and R.W. Sidwell. 1993. Antiherpesvirus activity and mode of action of SP-303, a novel plant flavonoid. Chemotherapy 39:203-211.
179. Barnard, D.L., J.H. Huffman, L.R. Meyerson, and R.W. Sidwell. 1993. Mode of inhibition of respiratory syncytial virus by a plant flavonoid, SP-303. Chemotherapy 39:212-217.
180. Barnard, D.L., J.H. Huffman, R.W. Sidwell, and E.J. Reist. 1993. Selective inhibition of cytomegaloviruses by 9-(3'-ethylphosphono-1'-hydroxymethyl-1'-propyloxymethyl)guanine. Antiviral Res. 22:77-89.
181. Huang, I.-J., E., Hayama, Y. J. Jeong, and J. K.-K. Li. 1993. Conservation of the segment 4 gene sequence and of a leucine zipper motif in VP4 among five US Bluetongue Viruses. Virology 195:7720739.
182. Hwang, G.-Y., and J. K.-K. Li. 1993. Identification and localization of a serotypic neutralization determinant of VP2 Protein of Bluetongue Virus 13. Virology 195:859-862.
183. Hwang, G.-Y., Y.-Y. Yang, and J. K.K. Li. 1993. High sequence conservation among the United States bluetongue viruses cognate M2 genes which encode the nonstructural NS1 tubule protein. Virology 192:321-327.
184. Kim, Y. W., J. K.-K. Li, and R. P. Sharma. 1993. Affinity of retinoids to recombinant retionoic acid receptors alfa, beta and gamma. Toxicologist 13:252.
185. Mead, J.R., R.A. Burger, J.D. Morrey, R.P. Warren, K. Okleberry, and R.W. Sidwell. 1993. Effect of immunomodulators in the hu-PBL-SCID mouse model. Biotechnol. Therapeut. 4:133-143.
186. Morrey, J.D., M.K. Jackson, T.D. Bunch, and R.W. Sidwell. 1993. Activation of the human immunodeficiency virus type-1 long termination repeat by skin-sensitizing chemicals in transgenic mice. Intervirology 36:65-71.
187. Sidwell, R.W., D.F. Smee, R.P. Warren, J.H. Huffman, B.J. Gilbert, R.A. Burger, and F.C. Pearson. 1993. Murine cytomegalovirus-inhibitory effects of ImuVert. Antiviral Res. 20:279-292.
188. Sidwell, R.W., J.D. Morrey, K.M. Okleberry, R.A. Burger, and R.P. Warren. 1993. Immunomodulator effects on the Friend virus infection in genetically defined mice. Ann. NY Acad. Sci. 685:432-446.
189. Smee, D.F., J. Gilbert, B.B. Barnett, J.W. Huggins, and R.W. Sidwell. 1993. Treatment of lethal Pichinde virus infections in weanling LVG/Lak hamsters with ribavirin, ribamidine, selenazofurin, and ampligen. Antiviral Res. 20:57-70.
190. Yang, Y.-Y., and J. K.-K. Li. 1993. Glycosylation of the major outer capsid protein of bluetongue viruses. Virology 194:350-354.
191. Gabrielsen, B., J.J. Kirsi, C.D. Kwong, D.A. Carter, C.A. Krauth, L.K. Hanna, J.W. Huggins, T.P. Monath, D.F. Kefauver, H.A. Blough, J.T. Rankin, C.M. Bartz, J.H. Huffman, D.F. Smee, R.W. Sidwell, W.M. Shannon and J.A. Secrist. 1994. In vitro and in vivo antiviral (RNA) evaluation of orotidine 5'-monophosphate decarboxylase inhibitors, including 6-azauridine-5'-(ethyl methoxyalaninyl)phosphate (a 5'-monophosphate prodrug). Antiviral Chem. & Chemother. 5:209-220.
192. Hayama, E., and J. K.-K. Li. 1994. Mapping and characterization of antigenic epitopes and the nucleic-binding domains of the VP6 proteins of bluetongue viruses. J. Virology 68:3604-3611.
193. Huffman, J.H., R.W. Sidwell, A.G. Morrison, J. Coombs, and E.J. Reist. 1994. Structure-activity relationship of phosphonic acid analogs of acyclovir or ganciclovir against human cytomegalovirus in MRC-5 cells. Nucleotides and Nucleosides 13:607-613.
194. Hwang, G.-Y., M. Xiang, and J. K.-K. Li. 1994. Analysis and conservation of the sequences among the cognate L3 segments of five U.S. Bluetongue viruses. Virus Research 32:381-389.
195. Kim, Y. W., J. K.-K. Li, and R. Sharma. 1994. Characterization of heterologously expressed recombinant retinoic acid receptors with natural and synthetic retinoids. J. Biochemical Toxicology 9:225-234.
196. Lillie, J.W., D.F. Smee, J.H. Huffman, L.J. Hansen, R.W. Sidwell, and R. Kaddurah-Daouk. 1994. Cyclocreatine (1-carboxymethyl - 2-iminoimidazolidine) inhibits the replication of human herpes virus. Antiviral Res. 23:203-218.
197. Morrey, J.D., S.M. Bourn, J.L.B. Morris, T.D. Bunch and R.W. Sidwell. 1994. Activation of the human immunodeficiency virus long terminal repeat by abrasion of the skin in transgenic mice. Intervirology 37:315-320.
198. Reist, E.J., W.W. Bradford, B.L. Ruhland-Fritsh, P.A. Sturm, N.T. Zaveri, J.H. Huffman and R.W. Sidwell. 1994. Synthesis of a cyclonucleoside phosphonates as antiviral agents against cytomegalovirus. Nucleosides & Nucleotides 13:539-550.
199. Sidwell, R.W., J.D. Morrey, and R.P. Warren. 1994. Cytokines as potential therapies for human immunodeficiency virus. Canad. J. Infect. Dis. 5(suppl. A):28-35.
200. Sidwell, R.W., J.D. Morrey, R.P. Warren, R.A. Burger, K. Okleberry, I.S. Sim, and M. Hitchcock. 1994. Effect of the combination of human recombinant interferon-α-A/D and 2',3'-didehydro-2',3'-dideoxythymidine (D4T) on murine retrovirus disease. Rec. Adv. Chemother. 1:650-651.
201. Sidwell, R.W., J.H. Huffman, B.J. Moscon, and R.P. Warren. 1994. Influenza virus-inhibitory effects of intraperitoneal- and aerosol-administered SP-303, a plant flavonoid. Chemotherapy 40:42-50.
202. Sidwell, R.W., J.H. Huffman, D.L. Barnard, D.F. Smee, R.O. Warren, M.A. Chirigos, M. Kende and H. Huggins. 1994. Antiviral and immunomodulating inhibitors of experimentally induced Punta Toro Virus infections. Antiviral Res. 25:105-122.
203. Ubillas, R., S.D. Jolad, R.C. Bruening, M.R. Kernan, S.R. King, D.F. Sesin, MN. Barrett, C.A. Stoddart, T. Flaster, J. Kuo, F. Ayala, E. Meza, M. Castañel, D. McMeekin, E. Rozhon, M.S. Tempesta, D. Barnard, J. Huffman, D. Smee, R. Sidwell, K. Soike, A. Brazier, S. Safrin, R. Orlando, P.T.M. Kenny, N. Berova and K. Nakanishi. 1994. SP-303, an antiviral oligomeric proanthocyanidin from the latex of Croton lechleri (Sangre de Drago). Phytomedicine 1:77-106.
204. Warren, R.P. and R.W. Sidwell. 1994. The potential role of cytokines in the treatment of viral infections. Clin. Immunother. 1:15-30.
205. Barnard, D.L., D.W Fairbaine, K.L. O’Neill, T.L. Gage and R.W. Sidwell. 1995. Anti-human cytomegalovirus activity and toxicity of sulfonated anthraquinones and anthraquinone derivatives. Antiviral Res. 28:317-329.
206. Barnett, B.B., D.F. Smee, S. Malek and R.W. Sidwell. 1995. Selective cytotoxicity towards cytomegalovirus-infected cells by immunotoxins consisting of gelonin linked to anti-cytomegalovirus antibody. Antiviral Res. 28:93-100.
207. Burger, R.A., R.P. Warren, J.H. Huffman and R.W. Sidwell. 1995. Effect of methionine enkephalin on natural killer cell and cytotoxic T lymphocyte activity in mice infected with influenza A virus. Immunopharmacol. Immunotoxicol. 17:323-334.
208. Chirigos, M.A., E. Talor, R.W. Sidwell, R.A. Burger, and R.P. Warren. 1995. Leukocyte interleukin, inj. (LI) augmentation of natural killer cells and cytotoxic T-lymphocytes. Immunopharmacol. Immunotoxicol. 17:247-264.
209. Huang, I.-J., G.-Y. Hwang, Y.-Y. Yang, E. Hayama, and J. K.-K. Li. 1995. Sequence analysis and antigenic epitopes mapping of the putative RNA-Directed RNA polymerase genes of five US bluetongue viruses. Virology 214:280-288.
210. Kimberlin, D.W., E.R. Kern, R.W. Sidwell, T.W. North and R.I. Whitley. 1995. Models of antiviral resistance. Antiviral Res. 26:415-422.
211. Sidwell, R.W., D.F. Smee, J.H. Huffman, K.W. Bailey, R.P. Warren, R.A. Burger, and C.L. Penney. 1995. Antiviral activity of an immunomodulatory lipophilic desmuramyl dipeptide analog. Antiviral Res. 26:145-159.
212. Sidwell, R.W., J.H. Huffman, D.L. Barnard, D.F. Smee, R.P. Warren, M. Kende and J.W. Huggins. 1995. Murine Punta Toro virus infection: A potential model for study of hantavirus inhibitors. Internat. Antiviral News 3:34-36.
213. Sidwell, R.W., K.W. Bailey, M.H. Wong and J. Huffman. 1995. In vitro and in vivo sensitivity of a non-mouse-adapted influenza A (Beijing) virus infection to amantadine and ribavirin. Chemotherapy 41: 455-61.
214. Sidwell, R.W., R.P. Warren, K. Okleberry, R.A. Burger, and J.D. Morrey. 1995. Effect of the combination of interferon-α-A/D and stavudine on Friend virus infections in (B10.A x A.By)F1 mice. J. Infect. Dis. 171:S93-98.
215. Smee, D.F, B.B. Barnett, R.W. Sidwell, E.J. Reist, and A. Holy. 1995. Antiviral activities of nucleosides and nucleotides against wild-type and drug-resistant strains of murine cytomegalovirus. Antiviral Res. 26:1-9.
216. Smee, D.F., R.W. Sidwell and B.B Barnett. 1995. Combination of antiviral immunotoxin and ganciclovir or cidofovir for the treatment of murine cytomegalovirus infection. Antiviral Res. 32:165-171.
217. Smee, D.F., S.T. Sugiyama, R.W. Sidwell and B.B. Barnett. 1995. Effects of monoclonal antibody combined with ganciclovir or (5)-1-[3-hydroxy-(2-phosphonylmethoxy) propyl] cytosine against murine cytomegalovirus infections in cell culture and in severe combined immunodeficient mice. Chemotherapy 41:141-148.
218. Barnett, B.B., D.F. Smee and R.W. Sidwell. 1996. Selective cytotoxicity of ricin A chain immunotoxin, towards murine cytomegalovirus-infected cells. Antimicrob. Ag. Chemother. (40: 470-472).
219. Sidwell, R.W. 1996. Ribavirin: A review of antiviral efficacy, Recent Res. Devel. in Antimicrob. Agents and Chemother. (G. Pandalai, ed.) Research Signpost: Kerala, India. 1:219-256.
220. Sidwell, R.W., J.H. Huffman, K.W. Bailey, M.H. Wong, A. Nimrod and A. Panet. 1996. Inhibitory effects of recombinant manganese superoxide dismutase on influenza virus infections in mice. Antimicrob. Ag. Chemother. 11:2626-2631.
221. Smee, D.F., R.W. Sidwell, J.H. Huffman, J.W. Huggins, M. Kende, and A.J. Verbiscar. 1996. Antiviral activities of tragacanthin polysaccharides on Punta Toro virus infections in mice. Chemotherapy 42:286-293.
222. Wang, L.-F., A. D. Hyatt, P. L. Whiteley, M. Andrew, J. K.-K. Li, and B. T. Eaton. 1996. Topography and immunogenicity of bluetongue virus VP7 epitopes. Archieves fur Virologie 141:111-123.
223. Barnard, D.L., C.L. Hill, T. Gage, J.E. Matheson, J.H. Huffman, R.W. Sidwell, M.I. Otto, R.F. Schinazi. 1997. Potent inhibition of respiratory syncytial virus by polyoxometalates of several structural classes. Antiviral Res. 34:27-37.
224. Barnard, D.L., N. Bischofberger, C.U. Kim, J.H. Huffman, R.W. Sidwell, J.P. Dougherty, W. Lew, M.A. Williams and W. Yang. 1997. Acyclic phosphonomethylether nucleoside inhibitors of respiratory viruses. Antiviral Chem. & Chemother. 8:223-233.
225. Huang, I.-J., and J. K.-K. Li. 1997. Purification of the putative guanylytransferase of bluetongue virus from both eukaryotic and prokaryotic expression system. Int. J. Bio-Chromatography 3:143-154.
226. Huffman, J.H., R.W. Sidwell, D.L. Barnard, A. Morrison, M.J. Otto, C.L. Hill and R.F. Schinazi. 1997. Influenza virus-inhibitory effects of a series of germanium- and silicon-centred polyoxometalates. Antiviral Chem. & Chemother. 8:75-83.
227. Judd, Amrit K.A. Sanchez, D.J. Bucher, J.H. Huffman, K. Bailey, and R.W. Sidwell. 1997. In vivo anti-influenza virus activity of a zinc finger peptide. Antimicrob. Ag. & Chemother. 41:687-692.
228. Sidwell, R.W. 1997. Utah State University’s Instutute for Antiviral Research. Int’l Antiviral News. 5:186-189.
229. Smee, D.F., R.A. Burger, R.D. Lourren, K.W. Bailey and R.W. Sidwell. 1997. An immunosuppressed mouse model of lethal murine gammaherpesvirus 68 infection for studying potential treatment of Epstein-Barr virus infection in man. Antiviral Chem. and Chemother. 8:573-581.
230. Fatemi, S. H., R. W. Sidwell, D. Kist, P. Akhter, K. Bailey, P. Thuras, and J. Sedgwick. 1998. Differential expression of synaptosome-associated protein 23 Kda [SNAP-25] in hippocampi of neonatal mice following exposure to human influenza virus in utero. Brain Res. 800:1-9.
231. Fatemi, S. H., R. W. Sidwell, P. Akhter, J. Sedgewick, P. Thuras and K. Bailey. 1998. Human influenza viral infections in vitro increase nNOS expression in hippocampi of neonatal mice. Synapse 29:84-88.
232. Mendel, D. B. and R. W. Sidwell. 1998. Influenza virus resistance to neuraminidase inhibitors. Drug Resistance Update. 1:184-189.
233. Mendel, D.B., C.Y. Tai, P.A. Escarpe, W. Li, R.W. Sidwell, J.H. Huffman, C. Sweet, K.J. Jakeman, J. Merson, S.A. Lacy, W. Lew, M.A. Williams, L. Zhang, M.S. Chen, N. Bishofberger and C.U. Kim. 1998. Oral administration of a novel, potent influenza neuraminidase inhibitor protects mice and ferrets against influenza infection. Antimicrob. Agents Chemother. 42:640-646.
234. Morrey, J. D. and R. W. Sidwell. 1998. Transgenic mice as a chemotherapeutic model for HBV infections. In: R. F. Schinzai, J. P. Sommadossi, and H. Thomas (eds.) Therapies of Viral Hepatitis. Int’l Med. Press, New York pp. 161-170.
235. Morrey, J. D., K. W. Bailey, B. A. Korba and R. W. Sidwell. 1998. Utilization of transgenic mice replicating high levels of hepatitis B virus for antiviral evaluation of lamivudine. Antiviral Res. 42:97-108.
236. Morrey, J. D., B. E. Korba, and R. W. Sidwell. 1998. Transgenic mice as a chemotherapeutic model for hepatitis B virus infection. Antiviral Therapy 3:59-68.
237. Player, M. R., D. L. Barnard, and P. F. Torrence. 1998. Potent inhibition of respiratory syncytial virus replication using a 2-5A-antisense chimera targeted to signals within the virus genomic RNA. Proc. Nat'l. Acad. USA. 95:8874-8879.
238. Sidwell, R.W., J.H. Huffman, D.L. Barnard, K.W. Bailey, M.H. Wong, A. Morrison, T. Syndergaard and C.U. Kim. 1998. Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor. Antiviral Res. 37:107-120.
239. Tai, C. Y., P. A. Escarpe, R. W. Sidwell, M. A. Williams, W. Lew, H. Wu, C. U. Kim, and D. B. Mendel. 1998. Characterization of human influenza virus variants selected in vitro in the presence of the neuraminidase inhibitor GS4071. Antimicrob. Ag. Chemother. 42:3234-3241.
240. Barnard, D. L., R. W. Sidwell, W. Xiao, M. R. Player, S. Adah, and P. F. Torrence. 1999. 2-5A-Antisense inhibition of respiratory syncytial virus replication: Effects of oligonucleotide structure modifications and RNA target site selection. Antiviral Res. 41:119-134.
241. Bedard, J., S. May, M. Lis, L. Tryphonas, J. Drach, R. Sidwell, L. Chan, T. Bowline, R. Rando. 1999. Comparative study of the anti-HCMV activity and toxicity of a tetrahydrofuran phosphonate analogue of guanosine and HPMPC. Antimicrob. Ag. Chemother. 43:557-567.
242. Fatemi, S. H., E. S. Emamian, D. Kist, R. W. Sidwell, K. Nakajima, P. Akhter, A. Shier, S. Sheikh, and K. Bailey. 1999. Defective corticogenesis and reduction in Reelin immunoreactivity in cortex and hippocampus of prenatally infected neonatal mice. Molecular Psychiatry 4:145-154.
243. Jackson M. K., E. A. Mitchell, S. G. Winslow, K. M. Okelberry, R. W. Sidwell and J. D. Morrey. 1999. Resistance to Friend leukemia virus in transgenic mice expressing the native FV-4 gene. Acta virologica 43:19-23.
244. Lin, Y-M., M. T. Flavin, R. Schure, F-C. Chen, R. W. Sidwell, D. L. Barnard, J. H. Huffman, and R. R. Kern. 1999. Antiviral activities of biflavonoids. Planta Med. 65:120-125.
245. Morrey, J. D., R. W. Sidwell and B. A. Korba. 1999. Animal models for HBV infection-transgenic mice. In: O. Zak and M. Sande (eds.) Handbook of Animal Models of Infection. Academic, London pp. 1009-1019.
246. Sidwell, R. W. 1999. Ribavirin: Immunomodulatory effects. Intn’l Antiviral News 7:2.
247. Sidwell, R. W. 1999. The mouse model of influenza virus infection. In: O. Zak and M. Sande (eds.) Handbook of Animal Models of Infection. Academic, London pp. 981-987.
248. Sidwell, R. W., K. W. Bailey, P. A. Bemis, M. H. Wong, E. J. Eisenberg, and J. H. Huffman. 1999. Influence of treatment schedule and viral dose on the in vivo influenza-inhibitory effects of the orally administered neuraminidase inhibitor GS4104. Antiviral Chem. & Chemother. 10:187-193.
249. Burger, R. A., J. L. Billingsley, J. H. Huffman, K. W. Bailey, C. U. Kim, and R. W. Sidwell. 2000. Immunological effects of the orally administered neuraminidase inhibitor GS4104 in influenza virus-infected and uninfected mice. Immunopharmacology. 47:45-52.
250. Sidwell, R. W., and D. F. Smee. 2000. In vitro and in vivo assay systems for study of influenza virus inhibitors. Antiviral Res. 48:1-16.
251. Smee, D. F., and R. W. Sidwell. 2000. Respiratory infection models in mice for studying potential treatments of variola (smallpox) and monkeypox virus infections acquired through biowarfare or bioterrorism. Int’l Antiviral News. 8:123-127.
252. Yasuda, S., J. H. Huffman, D. F. Smee, R. W. Sidwell, and K. Miyata. 2000. Spectrum of virus inhibition by consensus interferon YM643. Antiviral Chem. and Chemother. 11:261-271.
253. Smee, D. F., K. W. Bailey, and R. W. Sidwell. 2000. Treatment of cowpox virus respiratory infections in mice with ribavirin as a single agent or followed sequentially by cidofovir. Antiviral Chem. and Chemother. 11:303-9.
254. Smee, D. F., K. W. Bailey, M. H. Wong, and R. W. Sidwell. 2000. Intranasal treatment of cowpox respiratory infections in mice with cidofovir. Antiviral Res. 47:171-178.
255. Smee, D. F., Huffman, J. H., Morrison, A. C., Barnard, D. L., and Sidwell, R. W. 2000. Cyclopentane neuraminidase inhibitors with potent in vitro anti-influenza virus activity. Antimicrob. Agents Chemother. 45:743-748.
256. Sidwell, R. W., Smee, D. F., Huffman, J. H., Barnard, D. L., Bailey, K. W., Morrey, J. D., and Babu, Y. S. 2000. In Vivo Influenza-Inhibitory Effects of the Cyclopentane Neuraminidase Inhibitor RWJ-270201. Antimicrob. Agents Chemother. 45:749-757.
257. Drusano, G. L., S. L. Preston, K. Bush, K. Bailey, and R. W. Sidwell. 2001. A pharmacodynamic evaluation of RWJ-270201, a novel neuraminidase inhibitor, in a lethal murine model of influenza predicts efficacy for once-daily dosing. Antimicrob. Agents Chemotherapy 45; 2115-2118.
258. Sidwell, R. W. 2001. A consideration of animal models used for study of influenza inhibitors. Proc. Options for Control of Influenza. pp. 835-838. Options for the Control of Influenza IV. International Congress Series 1219 (A. Osterhaus, N. Cox, and A. Hampton, eds.) Excerpta Medica, Amsterdam.
259. Sidwell, R. W., D. F. Smee, K. W. Bailey, and R. A. Burger. 2001. Primary immune system effects of the orally administered cyclopentane neuraminidase inhibitor RWJ-270201 in influenza virus-infected mice. Int’l. Immunopharmacology 1:1211-1218.
260. Sidwell, R.W., D.F. Smee, J.H. Huffman, D.L. Barnard, J.D. Morrey, K.W. Bailey, W.-C. Feng, Y.S. Babu, and K. Bush. 2001. Influence of virus strain, challenge dose, and time of therapy initiation on the in vivo influenza inhibitory effects of RWJ-270201. Antiviral Res. 51:179-187.
261. Morrey, J.D., D.F. Smee, R.W. Sidwell, and C. Tseng. 2002. Identification of active antiviral compounds against a New York isolate of West Nile virus. Antiviral Res. 55:107-116.
262. Barnard, D.L, Stowell, V., Seley, K.L., Hegde, V.R., Subha, R., Rajappan, P., Schneller, S.W. Smee, D.F. and Sidwell, R.W. 2001. Inhibition of measles virus replication by 5’-nor carbocyclic nucleoside analogs. Antiviral Chem. & Chemother. 12: 241-250.
263. Smee, D.F., K.W. Bailey, M.H. Wong, R.W. Sidwell. 2001. Effects of cidofovir on the pathogenesis of a lethal vaccinia virus respiratory infection in mice. Antiviral Res. 52:55-62.
264. Smee, D.F., K.W. Bailey, and R.W. Sidwell. 2001. Treatment of lethal vaccinia virus respiratory infections in mice with cidofovir. Antiviral Chem. and Chemother. 12: 71-76.
265. Song, C.Y., V. Paul, H. Choo, J. Morrey, R.W. Sidwell, R.F. Schinazi, and C.K. Chu. 2001. Enantiomeric synthesis of D- and L- cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile viruses. J. Med. Chem. 44:3985-3993.
266. Smee, D.F., R.W. Sidwell, A.C. Morrison, K.W. Bailey, E.Z. Baum, L. Ly, and P.C. Wagaman. 2001. Characterization of an influenza A (H3N2) virus resistant to the cyclopentane neuraminidase inhibitor RWJ-270201. Antiviral Res. 52: 251-259.
267. Sidwell, R.W., M.H. Wong, K.W. Bailey, D.L. Barnard, M.K. Jackson, and D.F. Smee. 2001. Utilization of alpha-1-acid glycoprotein levels in the serum as a parameter for in vivo assay of influenza virus inhibitors. Antiviral Chem. and Chemother. 12: 359-365.
268. Smee, D.F., K.W. Bailey, and R.W. Sidwell. 2001. Threatment of lethal vaccinia virus respiratory infection in mice with cidofovir. Antiviral Chem. and Chemother. 12: 71-76.
269. Sidwell, R.W., and D.F. Smee. 2002. Peramivir (BCX-1812. RWJ-270201): Potential new therapy for influenza. Expert Opinion on Investigational Drugs. 11: 859-869.
270. Smee, D.F., K.W. Bailey, A.C. Morrison, and R.W. Sidwell. 2002. Combination treatment of influenza A (H1N1) virus infections in cell culture and in mice with the cyclopentane neuraminidase inhibitor RWJ-270201 and ribavirin. Chemotherapy. 48: 88-93.
271. Julander, J.G., R.W. Sidwell, and J.D. Morrey. 2002. Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus. Antiviral Res. 55:27-40.
272. Sidwell, R.W., Allen, L.B., Huffman, J.H., Revankar, G.R., Robins, R.K., and Tolman, R.L. 1975. Viral keratitis-inhibitory effect of 9-β-D-arabinofuranosylhypoxanthine 5’-monophosphate. Antimicrob. Ag. Chemother. 8: 463-467.
273. Allen, L.B., Thompson, J.M., Huffman, J.H., Revankar, G.R., Tolman, R.L., Simon, L.N., Robins, R.K., and Sidwell, R.W. 1975. Inhibition of experimental deocyribonucleic acid virus-induced encephalitis by 9-β-D-arabinofuranosylhypoxanthine 5’-monophosphate. Antimicrob. Ag. Chemother. 8:468-473.
274. Smee, D.F., K.W. Bailey, and R.W. Sidwell. 2002. Treatment of lethal cowpox virus respiratory infections in mice with 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine and its orally active diacetate ester prodrug. Antiviral Res. 54: 113-120.
275. Shi, L., S.H. Fatemi, R.W. Sidwell, and P.H. Patterson. 2003. Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J. Neurosci. 23: 297-302.
276. Smee, D.F. and R.W. Sidwell. 2002. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 57: 41-52.
277. Sidwell, R.W., and D.F. Smee. 2002. Viruses of the Bunya- and Togaviridae Families: Potential as bioterrorism agents and means of control. Antiviral Res. 57: 101-111.
278. Fatemi, S.H., J. Earle, R. Kanoda, D. Kist, E.S. Emamian, P.H. Patterson, L. Shi, and R. Sidwell. 2002. Prenatal viral infection leads to pyramidal cell atrophy and macrocephaly in adulthood: implications for genesis of autism and schizophrenia. Cell Mol. Neurobiol. 22: 25-33.
279. Smee, D.F., R.W. Sidwell, D. Kefauver, M. Bray, and J.W. Huggins. 2002. Characterization of wild-type and cidofovir resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses. Antimicrob. Agents Chemother. 46: 1329-1335.
280. Smee, D.F., A. Morrison, D. Barnard, and R. Sidwell. 2002. Comparison of colorimetric, fluorometric, and visual methods for determining anti-influenza (H1N1 and H3N2) virus activities and toxicities of compounds. J. Virol. Methods. 106: 71-79.
281. Barnard, D.L., Z.Q. Xu, V.D. Stowell, H. Yuan, D.F. Smee, R. Samy, R.W. Sidwell, M.K. Nielsen, L. Sun, H. Cao, A. Li, C. Quint, J. Diegnan, J. Crabb and M.T. Flavin. 2002. Coumarins and pyranocoumarins, potential novel pharmacophores for inhibition of measles virus replication. Antiviral Chem. and Chemother. 13: 39-59.
282. Zhang, N., N.M. Chen, R. Sood,
K. Kalicharran, A. Fattom, R.B. Naso, D.L. Barnard, R.W. Sidwell, and R.S. Hosmane.
2002. In vitro inhibition of the measles virus by novel ring-expanded
(‘Fat’) nucleoside analogues containing the imidazo[4,5-e]
[1,3]diazepine ring system. Bioorg. & Med. Chem. Ltrs. 12: 3391-4.
Institute for Antiviral Research
Utah State University
5600 Old Main Hill
Logan, UT 84322-5600
Tel: (435) 797-1902
or (435) 797-1888
Fax: (435) 797-3959
Email: RSidwell@cc.usu.edu